Prefrontal Theta Oscillations Are Modulated by Estradiol Status During Fear Recall and Extinction Recall
نویسندگان
چکیده
منابع مشابه
Theta and gamma oscillations during encoding predict subsequent recall.
Electrophysiological and hemodynamic measures of human brain activity have been shown to distinguish between episodes of encoding items that are later recalled versus those that are not recalled (Paller and Wagner, 2002). Using intracranial recordings from 793 widespread cortical and subcortical sites in 10 epileptic patients undergoing invasive monitoring, we compared oscillatory power at freq...
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While deficits in fear extinction recall have been suggested to underlie vulnerability to anxiety disorders in adolescents, the neurobiology of these deficits remain underexplored. Here we investigate the functional connectivity (FC) of the ventromedial prefrontal cortex (vmPFC) and dorsolateral PFC (dlPFC) underlying extinction recall in healthy adolescents, and assess associations between FC ...
متن کاملPrefrontal oscillations during recall of conditioned and extinguished fear in humans.
Human neuroimaging studies indicate that the anterior midcingulate cortex (AMC) and the ventromedial prefrontal cortex (vmPFC) play important roles in the expression and extinction of fear, respectively. Electrophysiological rodent studies further indicate that oscillatory neuronal activity in homolog regions (i.e., prelimbic and infralimbic cortices) changes during fear expression and fear ext...
متن کاملStress exposure prior to fear acquisition interacts with estradiol status to alter recall of fear extinction in humans.
Classical fear acquisition and extinction are important models for the etiology and treatment of anxiety disorders such as posttraumatic stress disorder (PTSD). Women are at a higher risk for PTSD than men. Levels of circulating 17-β estradiol (E2) in women have been linked to deficits in fear extinction and extinction recall. In PTSD, fear learning coincides with acute traumatic stress. Howeve...
متن کاملDelayed recall of fear extinction in rats with lesions of ventral medial prefrontal cortex.
Extinction of auditory fear conditioning is thought to form a new memory. We previously found that rats with vmPFC lesions could extinguish fear to the tone within a session, but showed no recall of extinction 24 h later. One interpretation is that the vmPFC is the sole storage site of extinction memory. However, it is also possible that lesioned rats were unable to retrieve extinction memory s...
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ژورنال
عنوان ژورنال: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
سال: 2021
ISSN: 2451-9022
DOI: 10.1016/j.bpsc.2021.02.011